High-Level Accumulation of Exogenous Small RNAs Not Affecting Endogenous Small RNA Biogenesis and Function in Plants

RNA silencing is a fundamental plant defence and gene control mechanism in plants that are directed by 20-24 nucleotide (nt) small interfering RNA (siRNA) and microRNA (miRNA).Infection of plants with viral pathogens or transformation of plants with RNA interference (RNAi) constructs is usually associated with high levels of exogenous siRNAs, but i

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Evaluating the predictive validity of four divergent thinking tasks for the originality of design product ideation

What factors predict the originality of domain-specific idea generation? Replicating and extending an earlier study using a Design Product Ideation task in an introductory university design course, the present research, grounded in the componential theory of creativity, assessed the relative contributions to originality of design ideation from five

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Feasibility and accuracy of ED frailty identification in older trauma patients: a prospective multi-centre study

Abstract Background The burden of frailty on older people is identifiable by its adverse effect on mortality, morbidity and long term functional and health outcomes.In patients suffering from a traumatic injury there is increasing evidence Foot that it is frailty rather than age that impacts greatest on these outcomes and that early identification

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